Short-acting Ambien-type drugs are supposed to have less respiratory-depression (not a good thing at high altitude) than Valium-class benzodiazopines.

The highly respected Institute for Altitude Medicine of Peter Hackett at Telluride specifically says:

For other sleep disturbances at altitude:

Ambien (zolpidem) 5-10 mg by mouth before bedtime as needed for sleep

Ambien CR (controlled release) 12.5 mg by mouth before bedtime as needed for sleep

Lunesta (eszopiclone) 1-3 mg by mouth before bedtime as needed for sleep


Inst Alt Med