I know personally the miracle relief of joint and back pain from taking dexamethasone although it is only temporary. The trade off of side effects cancel the overall benefit.Serious drug.It really heats up the debate about who should be attemting high altitude adventures like Everest. If one has to take drugs like Dex then should that person even be there in the first place? Are people who are not physically able to be at altitude being enticed to attempt 20K+ climbs because there are doctors giving drugs to overcome HACE and HAPE? I have a problem with that.Not only immune suppression but adrenal gland compromise make Dex a dangerous drug.It also masks pain and leads to joint degeneration by overriding the pain message of physical exertion.