I have discussed the use of Diamox with two of my primary care physicians neither knew much about the use of the drug for use in the mountains. In fact, the first one said take 250 mg. twice daily the entirety of my a seven day trip.
I've learned a lot on WPSMB and the rest of the internet since that first trip in 2001. My current dosing regiment is substantially different than the aforementioned and different from current orthodoxy but it works pretty well for me.
As for HAPE, I've seen one case in about 20 years coming to the Sierra. AMS continues to be a major issue.
