I think it would be a good idea to keep the dust and weather away from the camera. If you have glass in front of the camera and as long as you keep the glass clean it should be fine to look through it at 10x. We were running our Sebec Lake cam at 10x looking through a window pane at Borestone Mountain over the weekend.
If you are going to have a hole in the wall can't rain get on to it? Or is there something more I don't understand?
Here are two photos of the camera in the box.
