I've read about recommended dosages of diamox discussed in other threads, and the timing before hiking. Maybe this would be a good place to restate things. What's the typical regiment?
usual these days seems to be 125-250 twice daily. Larger doses probably offers not much more benefit, but nearly guarantees side effects. Other factor is not just dose, but when to take it and how long. Various opinions suggest begin the day before ascent or start the day of, and take it for a few days or as many as five along the way at each successive rise in sleeping altitude, etc, etc. Lots of ways to do it but not all well established. Here is a protocol often quoted:
High Altitude Tutorial Getting back to waggas post about the calf:Did you know that (1) babies (calves, humans, and some other animals) are very hypoxic in utero and at birth, so of course O2 helps pink them up. One of the compensations is production of fetal hemoglobin (hgb F) a temporary form that has a left-shifted oxygen dissociation curve, the very same physiological effect that hyperventilation and blowing off CO2 to raise blood ph has in high altitude climbers. (2) calves and young cattle are much more sensitive to altitude than humans. They have a pulmonary artery reactivity that causes them to have pulmonary hypertension at altitudes as low as 5,000 ft. This causes
Chronic Altitude Sickness (Brisket Disease). Selective breeding and medical testing for susceptible cattle is carried out in higher altitude states like Utah. They learned that hard way many years ago that bringing cattle from lower pasture states to higher ones caused them to die from Brisket Disease.
