My doctor, who has climbed Mount Whitney, always emphasizes acclimatization. She has also prescribed acetazolamide (Diamox) for several years. This year I had an opportunity to hike Mt. Whitney after a week of acclimatization and so didn't use any Diamox. I found the hike pleasant and the easiest for me in years. I have another opportunity to hike Whitney later this month (to celebrate my 67th birthday) but only have 3 or 4 days to acclimatize so I may use the Diamox this time.

P.S. Thanks TR for the great photos!