Very interesting! I'm relatively new to this forum so I missed this thread before.
I remember flying to Tunnel Meadow with my dad in his Bonanza sometime back in the '70s. From there we backpacked up to Johnson Lake and Funston Lake. It seemed very cool to buzz in and be deep in the wilderness before even starting to hike.
Thinking back, though, although I don't recall having any problems, flying up from sea level (LA) and going to 10k+ feet within a matter of hours sounds like a recipe for altitude sickness!