I'm basically saying the same thing but I have a slight different method. This is based on most folks who do Mt. Whitney come from SoCal. If they can get to Mt. Whitney, they can also get to White Mtn. or Langley to find out if elevation is going to be a problem and if it is they can do something about it.
To me and you, this is just another mountain. If we miss it for any reason, we know it will be there the next time we want to do it. However, for many of this is year's worth of planning, a ton of bucks and if they don't summit another year of disappointment. Wifey got really depressed after doing what is still her longest hike with the most gain but her day ended at Trail Crest.
After coming to the Sierra year after year and playing at these higher elevations, I know what to expect. I believe this to be as important as being acclimatized. Of course, I come after taking Diamox for 3 days and know enough not to push too hard the first couple of days in these mountains. I know if I do, I will not be able to eat and most likely sleep well that night but I know in the morning I'm going to be ok. That come from experience, experience most every SoCal noob can pick up just by visiting High Sierra or Whites a month to six weeks before their trip.
I love the Sierra in October. The peeps are semi-gone and it's cool to cold, which makes for great hiking in my mind. But, I have a ton of gear and clothes and prepared for most of what Mother Nature throws at me.